General Information
-
DRAMP ID
- DRAMP18679
-
Peptide Name
- Peptide 9 (Mollusca/molluscs/mollusks, invertebrates, animals)
-
Source
- Marine snail Rapana venosa
-
Family
- Not found
-
Gene
- Not found
-
Sequence
- FPPPGESAVDMSFFYALSNP
-
Sequence Length
- 20
-
UniProt Entry
- No entry found
-
Protein Existence
- Not found
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
-
Target Organism
-
- [Ref.21703315] Gram-positive bacterium: Staphylococcus aureus;
- Gram-negative bacterium: Klebsiella pneumoniae
-
Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
-
Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Not found
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP18679.
Physicochemical Information
-
Formula
- C102H141N21O30S
Absent Amino Acids
- CHIKQRTW
Common Amino Acids
- P
Mass
- 2173.42
PI
- 3.67
Basic Residues
- 0
Acidic Residues
- 2
Hydrophobic Residues
- 7
Net Charge
- -2
-
Boman Index
- -770
Hydrophobicity
- 0.045
Aliphatic Index
- 44
Half Life
-
- Mammalian:1.1 hour
- Yeast:3 min
- E.coli:2 min
Extinction Coefficient Cystines
- 1490
Absorbance 280nm
- 78.42
Polar Residues
- 6
DRAMP18679
Comments Information
Function
- Antibacterial activity against Gram-positive and Gram-negative bacterium.
Literature Information
- ·Literature 1
-
Title
- Antimicrobial proline-rich peptides from the hemolymph of marine snail Rapana venosa.
-
Pubmed ID
- 21703315
-
Reference
- Peptides. 2011 Jul;32(7):1477-83.
-
Author
- Dolashka P, Moshtanska V, Borisova V, Dolashki A, Stevanovic S, Dimanov T, Voelter W.