General Information

    • DRAMP ID

    • DRAMP18695

    • Peptide Name

    • Venom peptide 1 (Scorpions, animals)

    • Source

    • Tityus serrulatus (Brazilian scorpion)

    • Family

    • Belongs to the non-disulfide-bridged peptide (NDBP) superfamily. Short ant

    • Gene

    • Not found

    • Sequence

    • KHFGKDSNFPF

    • Sequence Length

    • 11

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP18695 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP18695.

Physicochemical Information

    • Formula

    • C63H86N16O16

    • Absent Amino Acids

    • ACEILMQRTVWY

    • Common Amino Acids

    • F

    • Mass

    • 1323.47

    • PI

    • 8.6

    • Basic Residues

    • 3

    • Acidic Residues

    • 1

    • Hydrophobic Residues

    • 3

    • Net Charge

    • +2

    • Boman Index

    • -2464

    • Hydrophobicity

    • -1.127

    • Aliphatic Index

    • 0

    • Half Life

      • Mammalian:1.3 hour
      • Yeast:3 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 3

DRAMP18695

Comments Information

    • Function

    • May be an antibacterial peptide.

    • Tissue specificity

    • Expressed by the venom gland.

Literature Information

  • ·Literature 1

    • Title

    • Tityus serrulatus venom peptidomics: assessing venom peptide diversity.

    • Reference

    • Toxicon. 2008 Oct;52(5):611-8.

    • Author

    • Rates B, Ferraz KK, Borges MH, Richardson M, De Lima ME, Pimenta AM.