• • DRAMP ID

  • DRAMP18712

• • Peptide Name

  • Styelin A (Tunicate, invertebrates, animals)

• • Source

  • Styela clava (Sea squirt)

• • Family

  • Belongs to the Cecropins family.

• • Gene

  • Not found

• • Sequence

  • GFGKAFHSVSNFAKKHKTA

• • Sequence Length

  • 19

• • UniProt Entry

  • P81469

• • Protein Existence

  • Protein level

• • Biological Activity

  • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-

• • Target Organism

  • • [Ref.9467865] Gram positive bacteria: Listeria monocytogenes EGD (MIC=2 µg/ml), Staphylococcus aureus 930918-3 (MIC=6 µg/ml), Enterococcus faecalis 94.132 (MIC=2 µg/ml);
    • Gram-negative bacteria: Pseudomonas aeruginosa MR 3007 (MIC=4 µg/ml), Escherichia coli ML-35p (MIC=2.7 µg/ml), Salmonella typhimurium 14028S (MIC=5 µg/ml).

• • Hemolytic Activity

  • • No hemolysis information or data found in the reference(s) presented in this entry

• • Cytotoxicity

  • • Not included yet

• • Binding Target

  • Not found

• • Linear/Cyclic

  • Not included yet

• • N-terminal Modification

  • Not included yet

• • C-terminal Modification

  • Not included yet

• • Nonterminal Modifications and Unusual Amino Acids

  • Not included yet

• • Stereochemistry

  • Not included yet

• • Structure

  • Helix

• • Structure Description

  • Not found

• • Helical Wheel Diagram

  • 

• • PDB ID

  • None

• Predicted Structure

• Please click DRAMP18712_predicted_structure.pdb to download.

DRAMP18712

• • Function

  • Bactericidal against several Gram-positive and Gram-negative bacteria.

• • Tissue specificity

  • Hemocytes and pharyngeal tissues.

• ·Literature 1

• • Title

  • Styelins, broad-spectrum antimicrobial peptides from the solitary tunicate, Styela clava.

• • Pubmed ID

  • 9467865

• • Reference

  • Comp. Biochem. Physiol. 1997; 118:515-521

• • Author

  • Lee IH, Cho Y, Lehrer RI.