• DRAMP ID

    • DRAMP18715
    • Peptide Name

    • Cathepsin G(77-83) (Human, primates, mammals, animals)
    • Source

    • Homo sapiens
    • Family

    • Belongs to the Cathepsin G 77-83 truncted peptide.
    • Gene

    • Not found
    • Sequence

    • HPQYNQR
    • Sequence Length

    • 7
    • UniProt Entry

    • No entry found
    • Protein Existence

    • Protein level
    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
    • Target Organism

    • No MICs found in DRAMP database
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP18715 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP18715.
    • Formula

    • C40H59N15O12
    • Absent Amino Acids

    • ACDEFGIKLMSTVW
    • Common Amino Acids

    • Q
    • Mass

    • 942
    • PI

    • 8.75
    • Basic Residues

    • 2
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 0
    • Net Charge

    • +2
    • Boman Index

    • -3744
    • Hydrophobicity

    • -3.014
    • Aliphatic Index

    • 0
    • Half Life

      • Mammalian:3.5 hour
      • Yeast:10 min
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 1490
    • Absorbance 280nm

    • 248.33
    • Polar Residues

    • 2

DRAMP18715

    • Function

    • Bactericidal activity against Gram-positive and Gram-negative bacteria.
  • ·Literature 1
    • Title

    • Identification of the primary antimicrobial domains in human neutrophil cathepsin G.
    • Reference

    • J Biol Chem. 1990 Aug 15;265(23):13584-8.
    • Author

    • Bangalore N, Travis J, Onunka VC, Pohl J, Shafer WM.