• DRAMP ID

    • DRAMP20772
    • Peptide Name

    • cPcAMP1/26 (ciliate, Protists)
    • Source

    • Paramecium caudatum
    • Family

    • Unknown
    • Gene

    • Pcamp1
    • Sequence

    • PPHKKKLAVYPVFLFYLFLSWFSLIV
    • Sequence Length

    • 26
    • Swiss_Prot Entry

    • No entry found
    • Evidence code

    • Unknown
    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
    • Target Organism

      • [Ref.26883426] cPcAMP1/26 was capable of markedly killing A. hydrophila and S. aureus (p < 0.05), with the bactericidal rates being 27.7%, 31.7% and 40.1% as well as 34.4%, 47.4% and 49.2%, respectively
    • Hemolytic activity

      • [Ref.26883426] cPcAMP1/26 showed little hemolytic activity towards human erythrocytes at 100 μg/ml
    • Binding Target

    • Unknown
    • Structure

    • Unknown
    • Structure Description

    • Unknown
    • DRAMP20772 helical wheel diagram
    • Formula

    • C164H238N32O31
    • Absent Amino Acids

    • CDEGMNQRT
    • Common Amino Acids

    • L
    • Mass

    • 3153.89
    • PI

    • 9.84
    • Basic Residues

    • 4
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 15
    • Boman Index

    • 2931
    • Hydrophobicity

    • 93.46
    • Aliphatic Index

    • 127.31
    • Half Life

      • Mammalian:>20 hour
      • Yeast:>20 hour
      • E.coli:?
    • Extinction Coefficient Cystines

    • 8480
    • Absorbance 280nm

    • 339.2
    • Polar Residues

    • 4

DRAMP20772

DRAMP20772 chydropathy plot
    • Function

    • cPcAMP1/26 was capable of markedly killing A. hydrophila and S. aureus (p < 0.05)
  • Literature 1
    • Reference

    • Dev Comp Immunol. 2016 Jul;60:53-65.
    • Author

    • Cui P, Dong Y, Li Z, Zhang Y, Zhang S.
    • Title

    • Identification and functional characterization of an uncharacterized antimicrobial peptide from a ciliate Paramecium caudatum.