• DRAMP ID

    • DRAMP20783
    • Peptide Name

    • Pleurain-M1 (Frogs,amphibians,animals)
    • Source

    • Nidirana pleuraden (Yunnan pond frog)
    • Family

    • Belongs to the frog skin active peptide (FSAP) family. Pleurain subfamily.
    • Gene

    • Unknown
    • Sequence

    • GLLDSVKEGLKKVAGQLLDTLKCKISGCTPA
    • Sequence Length

    • 31
    • Evidence code

    • Unknown
    • Biological Activity

    • Antibacterial, Antimicrobial, Anti-Gram+, Anti-Gram-
    • Target Organism

      • [Ref.19028675] Gram-negative bacteria: Escherichia coli (MIC=6.3 μg/ml);
      • Gram-positive bacteria: Staphylococcus aureus (MIC=6.3 μg/ml), Bacillus subtilis (MIC=25 μg/ml);
      • Yeast: Candida albicans(MIC=12.5 μg/ml).
    • Hemolytic activity

    • Unknown
    • Binding Target

    • Unknown
    • Structure

    • Unknown
    • Structure Description

    • Unknown
    • DRAMP20783 helical wheel diagram
    • Formula

    • C139H245N37O43S2
    • Absent Amino Acids

    • FHMNRWY
    • Common Amino Acids

    • L
    • Mass

    • 3186.82
    • PI

    • 8.79
    • Basic Residues

    • 5
    • Acidic Residues

    • 3
    • Hydrophobic Residues

    • 11
    • Boman Index

    • -1702
    • Hydrophobicity

    • 14.84
    • Aliphatic Index

    • 113.23
    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 125
    • Absorbance 280nm

    • 4.17
    • Polar Residues

    • 10

DRAMP20783

DRAMP20783 chydropathy plot
    • Function

    • Antimicrobial activity against Gram-positive bacteria, Gram-negative bacteria and fungi.
  • Literature 1
    • Reference

    • Mol Cell Proteomics. 2009 Mar;8(3):571-83.
    • Author

    • Yang H, Wang X, Liu X, Wu J, Liu C, Gong W, Zhao Z, Hong J, Lin D, Wang Y, Lai R.
    • Title

    • Antioxidant peptidomics reveals novel skin antioxidant system.