General Information

    • DRAMP ID

    • DRAMP20911

    • Peptide Name

    • Sm-AMP-X2

    • Source

    • Stellaria media (Common chickweed)

    • Family

    • Belongs to the

    • Gene

    • sm-amp-x

    • Sequence

    • CMSTRGDQARKICE

    • Sequence Length

    • 14

    • Protein Existence

    • protein level

Activity Information

    • Biological Activity

    • Antimicrobial, Antifungal

    • Target Organism

      • [Ref.24081691] Fungus: Alternaria alternata(IC50>32.0μM), Aspergillus niger(IC50=16.9±1.9μM), Bipolaris sorokiniana(IC50>32.0μM), Botrytis cinerea(IC50>32.0μM), Fusarium oxysporum(IC50=25.0±3.0μM), Fusarium solani(IC50=22.5±3.1μM), Phytophthora infestans(IC50>32.0μM), Pythium ultimum(IC50>32.0μM).

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

    • No cytotoxicity information found in the reference(s) presented

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Cyclic

    • N-terminal Modification

    • Free

    • C-terminal Modification

    • Free

    • Nonterminal Modifications and Unusual Amino Acids

    • Disulfide bond between Cys1 and Cys13

    • Stereochemistry

    • L

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP20911 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP20911.

Physicochemical Information

    • Formula

    • C61H108N22O22S3

    • Absent Amino Acids

    • FHLNPVWY

    • Common Amino Acids

    • CR

    • Mass

    • 1597.84

    • PI

    • 8.06

    • Basic Residues

    • 3

    • Acidic Residues

    • 2

    • Hydrophobic Residues

    • 2

    • Net Charge

    • +1

    • Boman Index

    • -4985

    • Hydrophobicity

    • -0.864

    • Aliphatic Index

    • 35

    • Half Life

      • Mammalian:1.2 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 125

    • Absorbance 280nm

    • 9.62

    • Polar Residues

    • 5

DRAMP20911

Comments Information

    • Function

    • The mature peptide has antifungal activities

Literature Information

  • ·Literature 1

    • Title

    • Novel antifungal

    • Reference

    • Plant Mol Biol. 2014 Jan;84(1-2):189-202. doi: 10.1007/s11103-013-0127-z. Epub 2013 Oct 1.

    • Author

    • Slavokhotova AA, Rogozhin EA, Musolyamov AK, Andreev YA, Oparin PB, Berkut AA, Vassilevski AA, Egorov TA, Grishin EV, Odintsova TI.