• • DRAMP ID

  • DRAMP29098

• • Peptide Name

  • ACWWP1

• • Source

  • Synthetic construct

• • Family

  • Not found

• • Gene

  • Not found

• • Sequence

  • GLSRLFTALK

• • Sequence Length

  • 10

• • UniProt Entry

  • No entry found

• • Protein Existence

  • Not found

• • Biological Activity

  • Antimicrobial, Antibacterial,Anti-Gram+, Anti-Gram-

• • Target Organism

  • • [Ref.25172690]Gram-positive bacteria:Staphylococcus aureus ATCC 25923(MIC=16 µg/ml); Bacillus subtilis ATCC 9372(MIC=16 µg/ml); Streptococcus pneumoniae ATCC 49619(MIC=64 µg/ml);
    • Gram-negative bacteria:Escherichia coli ATCC 25922(MIC=32 µg/ml); Shigella dysenteriae ATCC 51302(MIC=256 µg/ml); Pseudomonas aeruginosa ATCC 27853 (MIC=64 µg/ml); Salmonella typhimurium ATCC 50013(MIC=32 µg/ml).

• • Hemolytic Activity

  • • [Ref.25172690]non-toxic to mouse erythrocytes up to 512 µg/ml.

• • Cytotoxicity

  • No cytotoxicity information found in the reference(s) presented

• • Binding Target

  • liposomes

• • Linear/Cyclic

  • Linear

• • N-terminal Modification

  • Free

• • C-terminal Modification

  • Free

• • Nonterminal Modifications and Unusual Amino Acids

  • None

• • Stereochemistry

  • L

• • Structure

  • Not found

• • Structure Description

  • Not found

• • Helical Wheel Diagram

  • 

• • PDB ID

  • None

• Predicted Structure

• There is no predicted structure for DRAMP29098.

DRAMP29098

• • Function

  • The change in cell surface hydrophobicity and membrane-permeable action of the purified ACWWP1 may have contributed to the antibacterial effect.

• ·Literature 1

• • Title

  • Targeted separation of antibacterial peptide from protein hydrolysate of anchovy cooking wastewater by equilibrium dialysis.

• • Pubmed ID

  • 25172690

• • Reference

  • Food Chem. 2015 Feb 1;168:115-23.

• • Author

  • Tang W, Zhang H, Wang L, Qian H, Qi X.