• • DRAMP ID

  • DRAMP29100

• • Peptide Name

  • Ascaphin-1 [F2I]

• • Source

  • Synthetic construct

• • Family

  • Not found

• • Gene

  • N/A

• • Sequence

  • GIRDVLKGAAKAFVKTVAGHIAN

• • Sequence Length

  • 23

• • UniProt Entry

  • P0CJ25

• • Protein Existence

  • Protein level

• • Biological Activity

  • Antimicrobial, Antibacterial,Anti-Gram-

• • Target Organism

  • • [Ref.19947578]Gram-negative bacteria:Escherichia coli ATCC 25922(MIC=4 µM).

• • Hemolytic Activity

  • • [Ref.19947578]25% hemolysis against human erythrocytes at 100 µM.

• • Cytotoxicity

  • No cytotoxicity information found in the reference(s) presented

• • Binding Target

  • liposomes

• • Linear/Cyclic

  • Linear

• • N-terminal Modification

  • Free

• • C-terminal Modification

  • Amidation

• • Nonterminal Modifications and Unusual Amino Acids

  • None

• • Stereochemistry

  • L

• • Structure

  • Not found

• • Structure Description

  • Not found

• • Helical Wheel Diagram

  • 

• • PDB ID

  • None

• Predicted Structure

• There is no predicted structure for DRAMP29100.

DRAMP29100

• • Function

  • Antibacterial activity against Gram-positive bacteria

• ·Literature 1

• • Title

  • Computational design of highly selective antimicrobial peptides.

• • Pubmed ID

  • 19947578

• • Reference

  • J Chem Inf Model. 2009 Dec;49(12):2873-82.

• • Author

  • Juretić D, Vukicević D, Ilić N, Antcheva N, Tossi A.