General Information

    • DRAMP ID

    • DRAMP37201

    • Peptide Name

    • Scolopin-2-NH2 (S-2-N)

    • Source

    • Sythetic

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • GILKKFMLHRGTKVYKMRTLSKRSH

    • Sequence Length

    • 25

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-

    • Target Organism

      • Gram-positive bacteria: Staphylococcus aureus (MIC=15μmol/L), Bacillus subtilis(MIC=21μmol/L)
      • Gram-negative bacteria: Escherichia coli(K2Ds1) (MIC=10μmol/L), Salmonella (MIC=15μmol/L).

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

    • No cytotoxicity information found in the reference(s) presented

    • Binding Target

    • Cell membrane, DNA

Structure Information

    • Linear/Cyclic

    • Linear

    • N-terminal Modification

    • Free

    • C-terminal Modification

    • Amidation

    • Nonterminal Modifications and Unusual Amino Acids

    • None

    • Stereochemistry

    • L

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Predicted Structure

    • There is no predicted structure for DRAMP37201.

Literature Information

  • ·Literature 1

    • Title

    • 少棘蜈蚣抗菌肽Scolopin 2-NH2的抗菌作用机制研究; Mechanism of Antimicrobial Peptide Scolopin 2-NH2 Isolated from Scolopendra subspinipes mutilans

    • doi

    • 10.13560/j.cnki.biotech.bull.1985.2018-0476.

    • Reference

    • [J].生物技术通报,2018,34(11):179-190.DOI:10.13560/j.cnki.biotech.bull.1985.2018-0476.

    • Author

    • 卢佳,邓秋萍,任文华:LU Jia,DENG Qiu-ping,REN Wen-hua