General Information

    • DRAMP ID

    • DRAMP37212

    • Peptide Name

    • hBD3(humanβdefensin3, hBD3)

    • Source

    • Homo sapiens

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • GIINTLQKYYCRVRGGRCAVLSCLPKEEQIGKCSTRGRKCCRRKK

    • Sequence Length

    • 45

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-

    • Target Organism

      • Gram-negative bacteria: Pseudomonas aeruginosa PAO1(MIC=32μg/mL), Klebsiella Pneumoniae(MIC=22.3μg/mL).

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

    • No cytotoxicity information found in the reference(s) presented

    • Binding Target

    • Cell membrane

Structure Information

    • Linear/Cyclic

    • Linear

    • N-terminal Modification

    • Free

    • C-terminal Modification

    • Free

    • Nonterminal Modifications and Unusual Amino Acids

    • None

    • Stereochemistry

    • L

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Predicted Structure

    • There is no predicted structure for DRAMP37212.

Literature Information

  • ·Literature 1

    • Title

    • 抗菌肽人β防御素3对铜绿假单胞菌PAO-1株的抑制作用; The Inhibition on Pseudomonas Aeruginosa PAO-1 by Antimirobial Peptide Human β Defensin 3

    • doi

    • 10.13241/j.cnki.pmb.2014.32.006.

    • Reference

    • [J].现代生物医学进展,2014,14(32):6225-6228.DOI:10.13241/j.cnki.pmb.2014.32.006.

    • Author

    • 宋珍,李镛,阴振晨,李擎天: SONG Zhen,LI Yong,YIN,Zhen-chen,LI Qing-tian