General Information

    • DRAMP ID

    • DRAMP37219

    • Peptide Name

    • CeAP1

    • Source

    • Centruroides exilicauda

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • FFGLIPGLVGSLISAFK

    • Sequence Length

    • 17

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+

    • Target Organism

      • Gram-positive bacteria: Staphylococcus aureus AB 94004 (MIC=16.0 µM), Bacillus.megaterium AB 90008(MIC=32.0 µM).

    • Hemolytic Activity

      • HD50 = 52.0 μM against on human red blood cells . 1% Triton X-100 were used as the positive control.

    • Cytotoxicity

    • No cytotoxicity information found in the reference(s) presented

    • Binding Target

    • DNA, RNA

Structure Information

    • Linear/Cyclic

    • Linear

    • N-terminal Modification

    • Random coil

    • C-terminal Modification

    • Random coil

    • Nonterminal Modifications and Unusual Amino Acids

    • None

    • Stereochemistry

    • L

    • Structure

    • Alpha helix

    • Structure Description

    • Amphiphilic α-helix structure. no helix structure in aqueous environment, induced into α-helix structure in hydrophobic environment.

    • Predicted Structure

    • There is no predicted structure for DRAMP37219.

Literature Information

  • ·Literature 1

    • Title

    • 蝎毒素抗菌肽CeAP1的生物信息学分析与生物活性鉴定; Functional identification and bioinformatics analysis of antimicrobial peptide Ce AP1 from scorpion venom

    • doi

    • 10.13350/j.cjpb.240202.

    • Reference

    • Journal of Pathogen Biology. 2024 Feb;19(2):130-136

    • Author

    • 敖日格乐,胡和珠拉,胡伊力格其,曾宪春:Aorigele,Huhezhula,Huyiligeqi,ZENG Xianchun