General Information

    • DRAMP ID

    • DRAMP37239

    • Peptide Name

    • GV(Designed with GRX2RX3RX2RG as template)

    • Source

    • Sythetic

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • GRVVRVVVRVVRG

    • Sequence Length

    • 13

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-

    • Target Organism

      • Gram-positive bacteria: Staphylococcus aureus ATCC 29213(MIC=4μmol/L), Staphylococcus aureus ATCC 43300(MIC=2μmol/L), Staphylococcus epidermidis ATCC 12228(MIC=8μmol/L), Bacillus subtilis CMCC 63501 (MIC=4μmol/L)
      • Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=2μmol/L), Escherichia coli UB1005 (MIC=2μmol/L), S.Typhimurium ATCC 7731(MIC=4μmol/L), Pseudomonas aeruginosa 27853(MIC=8μmol/L), S.pullorum C7913(MIC=4μmol/L).

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

    • No cytotoxicity information found in the reference(s) presented

    • Binding Target

    • Cell membrane

Structure Information

    • Linear/Cyclic

    • Linear

    • N-terminal Modification

    • Free

    • C-terminal Modification

    • Free

    • Nonterminal Modifications and Unusual Amino Acids

    • None

    • Stereochemistry

    • L

    • Structure

    • Alpha helix(In TFE)

    • Structure Description

    • Not found

    • Predicted Structure

    • There is no predicted structure for DRAMP37239.

Literature Information

  • ·Literature 1

    • Title

    • 不同疏水性氨基酸对α-螺旋抗菌肽生物学活性的影响; Effect of Different Hydrophobic Amino Acids on Biological Activity of Alpha Helix Antimicrobial Peptides

    • doi

    • 10.11843/j.issn.03666964.2019.04.012

    • Reference

    • [J].畜牧兽医学报,2019,50(04):791-801.

    • Author

    • 徐欣瑶,董娜,李欣然,杨洋,王志华,单安山: XU Xinyao,DONG Na,LI Xinran,YANG Yang,WANG Zhihua,SHAN Anshan