General Information

    • DRAMP ID

    • DRAMP37257

    • Peptide Name

    • Tat (49-57)

    • Source

    • Sythetic

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • RKKRRQRRR

    • Sequence Length

    • 9

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-

    • Target Organism

      • Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=90.70μg/mL), Bacillus subtilis KCTC 3068 (MIC=34.84μg/mL)
      • Gram-negative bacteria: Escherichia coli 25922 (MIC=20.63μg/mL), Salmonella typhimurium CMCC 50013 (MIC=146.36μg/mL).

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

    • No cytotoxicity information found in the reference(s) presented

    • Binding Target

    • DNA

Structure Information

    • Linear/Cyclic

    • Linear

    • N-terminal Modification

    • Free

    • C-terminal Modification

    • Free

    • Nonterminal Modifications and Unusual Amino Acids

    • None

    • Stereochemistry

    • L

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Predicted Structure

    • There is no predicted structure for DRAMP37257.

Literature Information

  • ·Literature 1

    • Title

    • 基于Tat(49-57)抗菌肽的设计、合成与性质研究; Design, Synthesis and Properties of the Antibacterial Peptides Based on Tat (49-57)

    • doi

    • 10.6023/cjoc201708042

    • Reference

    • [J].有机化学,2018,38(01):148-155.

    • Author

    • 吕名秀,买文鹏,卢奎,段冰潮,赵玉芬:Lü,Mingxiu Mai,Wenpeng Lu,Kui Duan,Bingchao Zhao,Yufen