General Information

    • DRAMP ID

    • DRAMP37286

    • Peptide Name

    • SpCrus1a29-47

    • Source

    • Scylla paramamosain

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • CRSWCKRPGHPEKNAFYCC

    • Sequence Length

    • 19

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-

    • Target Organism

      • Gram-positive bacteria: Staphylococcus aureus CGMCC 1.363 (MIC=6-12 µM);Micrococcus luteus CGMCC 1.290 (MIC=6-12 µM)
      • Gram-negative bacteria: Escherichia coli CGMCC 1.2389 (MIC＞48 µM).

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

    • No cytotoxicity information found in the reference(s) presented

    • Binding Target

    • Cell membrane

Structure Information

    • Linear/Cyclic

    • Linear

    • N-terminal Modification

    • Free

    • C-terminal Modification

    • WAP domain(8 conserved cysteines)

    • Nonterminal Modifications and Unusual Amino Acids

    • None

    • Stereochemistry

    • L

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Predicted Structure

    • There is no predicted structure for DRAMP37286.

Literature Information

  • ·Literature 1

    • Title

    • 拟穴青蟹抗菌肽Crustin新变体的表达特性与抗菌功能;Characterization of expression and antimicrobial activity of a novel Crustin isoform from Scylla paramamosain

    • doi

    • 10.6043/j.issn.0438-0479.201808007

    • Reference

    • j.issn.0438-0479

    • Author

    • 王晓飞,彭会,陈芳奕,张财亮,黄文树:WANG Xiaofei,PENG Hui,CHEN Fangyi,ZHANG Cailiang,HUANG Wenshu