• DRAMP ID

    • DRAMP37364
    • Peptide Name

    • LP-M4(Derived from Lausporin-1)
    • Source

    • Sythetic
    • Family

    • Not found
    • Gene

    • Not found
    • Sequence

    • FLSRLWRVAKRLF
    • Sequence Length

    • 13
    • UniProt Entry

    • No entry found
    • Protein Existence

    • Not found
    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
    • Target Organism

      • Gram-positive bacteria: Staphylococcus aureus ATCC 29213(MIC=5μmol/L), Staphylococcus aureus ATCC 25923(MIC=10μmol/L), Enterococcus faecalis ATCC 29212(MIC=5μmol/L)
      • Gram-negative bacteria: Escherichia coli ATCC 25922(MIC=5μmol/L, Escherichia coli ATCC 35218(MIC=10μmol/L), Pseudomonas aeruginosa ATCC 27853(MIC=10μmol/L), Klebsiella pneumoniae ATCC 27853(MIC=10μmol/L),acinetobacter baumannii ATCC 19606(MIC=5μmol/L)
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

    • No cytotoxicity information found in the reference(s) presented
    • Binding Target

    • Cell membrane
    • Linear/Cyclic

    • Linear
    • N-terminal Modification

    • Free
    • C-terminal Modification

    • Free
    • Nonterminal Modifications and Unusual Amino Acids

    • None
    • Stereochemistry

    • L
    • Structure

    • Not found
    • Structure Description

    • Cationic α-helical antimicrobial peptide composed of 17 amino acid residues
    • Predicted Structure

    • There is no predicted structure for DRAMP37364.
  • ·Literature 1
    • Title

    • 基于蝎抗菌肽Lausporin-1设计衍生肽以优化其抗“ESKAPE”病原菌活性:Analogues Designed from Scorpion-Derived Peptide Lausporin-2 Exhibit Improved Antimicrobial Activity Against ‘ESKAPE’ Pathogens
    • doi

    • :10.13819/j.issn.2096-708X.2021.05.001.
    • Reference

    • [J].湖北医药学院学报,2021,40(05):441-445+453.DOI:10.13819/j.issn.2096-708X.2021.05.001.
    • Author

    • 罗旭东,张凯月,蒋僡雯: LUO Xu-dong ZHANG Kai-yue JIANG Hui-wen LI Fang-yan CHEN Zong-yun