• DRAMP ID

    • DRAMP29891
    • Peptide Name

    • O-12 (Oncocin)
    • Source

    • Synthetic construct
    • Family

    • Not found
    • Gene

    • Not found
    • Sequence

    • VDKPPYLPRPRPPRRIYNR-NHpr
    • Sequence Length

    • 19
    • UniProt Entry

    • No entry found
    • Protein Existence

    • Not found
    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
    • Target Organism

      • Gram-negative bacterium: Escherichia coli BL21AI(MIC=4 µg/ml);
      • Gram-positive bacteria: Micrococcus luteus ATCC 10240(MIC=8 µg/ml).
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

    • No cytotoxicity information found in the reference(s) presented
    • Binding Target

    • Not found
    • Serum or Protease Type

    • Mouse serum
    • Stability Data

    • The half-live is >120 min in 25% aqueous mouse serum.
    • Assay

    • Matrix-assisted laser desorption/ionisation–time-of-flight mass spectrometry (MALDI-TOF-MS)
    • Linear/Cyclic

    • Linear
    • N-terminal Modification

    • Free
    • C-terminal Modification

    • Propylamidation
    • Nonterminal Modifications and Unusual Amino Acids

    • Free
    • Stereochemistry

    • L
    • Structure

    • Not found
    • Structure Description

    • Not found
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP29891.
  • ·Literature 1
    • Title

    • Bactericidal oncocin derivatives with superior serum stabilities
    • Reference

    • Int J Antimicrob Agents. 2011 Feb;37(2):166-70.
    • Author

    • Knappe D, Kabankov N, Hoffmann R