• DRAMP ID

    • DRAMP29905
    • Peptide Name

    • PEG-TRI-1144
    • Source

    • Synthetic construct
    • Family

    • Not found
    • Gene

    • Not found
    • Sequence

    • TTWEAWDRAIAEYAARIEALLRALQEQQEKNEAALREL
    • Sequence Length

    • 38
    • UniProt Entry

    • No entry found
    • Protein Existence

    • Not found
    • Biological Activity

    • Antimicrobial, Antiviral
    • Target Organism

      • Virus: HIV type 2
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

    • No cytotoxicity information found in the reference(s) presented
    • Binding Target

    • Not found
    • Serum or Protease Type

    • Rat plasma, human plasma
    • Stability Data

    • The half life is 34h in rat plasma and 70h in human plasma.
    • Assay

    • LC-MS/MS
    • Linear/Cyclic

    • Linear
    • N-terminal Modification

    • Acetylation
    • C-terminal Modification

    • Amidation
    • Nonterminal Modifications and Unusual Amino Acids

    • Conjugated with PEG(40KDa) throµgh Lys-30
    • Stereochemistry

    • L
    • Structure

    • Not found
    • Structure Description

    • Not found
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP29905.
  • ·Literature 1
    • Title

    • Half-life extension of the HIV-fusion inhibitor peptide TRI-1144 using a novel linker technology. Eur J Pharm Biopharm
    • Reference

    • Eur J Pharm Biopharm. 2015 Jun;93:254-9.
    • Author

    • Schneider EL, Ashley GW, Dillen L, Stoops B, Austin NE, Malcolm BA, Santi DV.