General Information

    • DRAMP ID

    • DRAMP29911

    • Peptide Name

    • oSFTI

    • Source

    • Synthetic construct

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • GRCTKSIPPICYPD

    • Sequence Length

    • 14

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Anti-cancer

    • Target Organism

    • PC-3 or DU-145 prostate cancer cells.

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

    • No cytotoxicity information found in the reference(s) presented

    • Binding Target

    • Not found

Stability Information

    • Serum or Protease Type

    • Human Serum

    • Stability Data

    • The half-live is found to be 34.5h.

    • Assay

    • RP-HPLC

Structure Information

    • Linear/Cyclic

    • Cyclic

    • N-terminal Modification

    • Cyclization(Cys3 and Cys11)

    • C-terminal Modification

    • Cyclization(Cys3 and Cys11)

    • Nonterminal Modifications and Unusual Amino Acids

    • Disulfide bond between Cys3 and Cys11.

    • Stereochemistry

    • L

    • Structure

    • Not found

    • Structure Description

    • Not found

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP29911.

Literature Information

  • ·Literature 1

    • Title

    • Sunflower trypsin inhibitor 1 derivatives as molecular scaffolds for the development of novel peptidic radiopharmaceuticals

    • Reference

    • Mol Imaging Biol. 2010 Aug;12(4):377-85

    • Author

    • Boy RG, Mier W, Nothelfer EM, Altmann A, Eisenhut M, Kolmar H, Tomaszowski M, Krämer S, Haberkorn U.