• DRAMP ID

    • DRAMP29913
    • Peptide Name

    • CATH-2(C1-15)
    • Source

    • Synthetic construct
    • Family

    • Not found
    • Gene

    • Not found
    • Sequence

    • RFGRFLRKIRRFRPK
    • Sequence Length

    • 15
    • UniProt Entry

    • No entry found
    • Protein Existence

    • Not found
    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
    • Target Organism

    • No MICs found in DRAMP database
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

    • No cytotoxicity information found in the reference(s) presented
    • Binding Target

    • Not found
    • Serum or Protease Type

    • Human serum
    • Stability Data

    • The antibacterial activity of C1-15 decreased substantially after incubation for 1h in serum, with a complete abolishment after 2h
    • Assay

    • Radial diffusion assays
    • Linear/Cyclic

    • Linear
    • N-terminal Modification

    • Free
    • C-terminal Modification

    • Amidation
    • Nonterminal Modifications and Unusual Amino Acids

    • Free
    • Stereochemistry

    • L
    • Structure

    • Not found
    • Structure Description

    • Not found
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP29913.
  • ·Literature 1
    • Title

    • Improved proteolytic stability of chicken cathelicidin-2 derived peptides by D-amino acid substitutions and cyclization.
    • Reference

    • Peptides. 2011 May;32(5):875-80
    • Author

    • Molhoek EM, van Dijk A, Veldhuizen EJ, Haagsman HP, Bikker FJ.