clinical Information

    • DRAMP ID

    • DRAMP18067

    • Sequence

    • Structure not disclosed

    • Sequence Name

    • MX-594AN

    • Description

    • Indolicidin based

    • Activity

    • Antibacterial, Antifungal

    • Medical use

    • the treatment of catheter-related acne

    • Stage of Development

    • Phase IIb(Completed)

    • Comments

    • MX-594AN significantly reduced acne lesions compared with vehicle controls in a phase IIb trial in 2003 and was licensed to Cutanea Life Sciences in late 2005.

    • Company

    • Migenix (Vancouver, BritishColumbia, Canada)

    • Target Organism

      • No MICs found on DRAMP database

    • Reference

      • Cationic antimicrobial peptides in clinical development, with special focus on thanatin and heliomicin.Eur J Clin Microbiol Infect Dis (2012)(PMID: 21964560)