clinical Information
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DRAMP ID
- DRAMP18086
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Sequence
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Sequence Name
- Locilex
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Description
- the 22-amino acid magainin
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Activity
- Antibacterial
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Medical use
- Infections of diabetic foot ulcers
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Stage of Development
- Phase III(Failure)
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Comments
- This development candidate did not obtain FDA approval in 1999 despite demonstrating clinical benefit in a Phase III trial.
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Company
- Genaera
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Target Organism
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- No MICs found on DRAMP database
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Reference
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- Antimicrobial peptides: therapeutic potential. Expert Opin. Pharmacother. (2006).