clinical Information

    • DRAMP ID

    • DRAMP18086

    • Sequence

    • Sequence Name

    • Locilex

    • Description

    • the 22-amino acid magainin

    • Activity

    • Antibacterial

    • Medical use

    • Infections of diabetic foot ulcers

    • Stage of Development

    • Phase III(Failure)

    • Comments

    • This development candidate did not obtain FDA approval in 1999 despite demonstrating clinical benefit in a Phase III trial.

    • Company

    • Genaera

    • Target Organism

      • No MICs found on DRAMP database

    • Reference

      • Antimicrobial peptides: therapeutic potential. Expert Opin. Pharmacother. (2006).