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Sequence
- GIGKFLHSAKKFGKAXVGEXXNK
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Sequence Name
- Sequence 32 from Patent US 10464975
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Source
- Synthetic construct
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Patent Type
- Granted Patent
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Publication Date
- 2019-11-5
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Family Info
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CA2989311A1, WO2017004591A2, US20170015716A1, WO2017004591A3, AU2016287754A1
, IL256395D0, KR20180022971A, MX2017016251A, EP3317294A2, CN108026146A
, BR
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Patent Title
- Stabilized Anti-microbial Peptides
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Abstract
- The present invention provides methods of designing and making structurally stabilized anti-microbial peptides for the prophylaxis and treatment of infection. Methods are also disclosed for designing stabilized anti-microbial peptides that are selectively lytic/cytotoxic to bacteria, allowing for internal use of anti-microbial peptides without mammalian membrane disruption and cytotoxicity.