Sequence Information

    • DRAMP ID

    • DRAMP18095

    • Name

    • PTX006

    • Sequence

    • Description

    • N-acylated analog of PTX005

    • Activity

    • Unknown

    • Target Organism

      • Gram-negative bacteria:
        E. coli J96 (MIC90=0.08X10-6 M), E. coli H5 (MIC90=0.08X10-6 M), E. coli IA2 (MIC90=0.1X10-6 M), Pseudomonas aeruginosa (MIC90=0.03X10-6 M);
      • Gram-positive bacteria:
        Staphlococcus aureus MN8 (MIC90=0.07X10-6 M), Staphlococcus aureus MNHO (MIC90=0.06X10-6 M), Staphlococcus aureus Eaton (drug-resistant strains) (MIC90=0.16X10-6 M), Staphlococcus aureus Wilson (drug-resistant strains) (MIC90=3.2X10-6 M).

    • Reference

      • Antimicrobial peptides: therapeutic potential. Expert Opin. Pharmacother. (2006).

Clinical Information

    • Medical use

    • Broad-spectrum antimicrobial;Antiendotoxin

    • Company

    • PepTx

    • Stage of Development

    • Preclinical

    • Comments

    • No more comments

    • Clinical Trials