Sequence Information

    • DRAMP ID

    • DRAMP18161

    • Name

    • OP-145 (AMP60.4Ac)

    • Sequence

    • IGKEFKRIVERIKRFLRELVRPLR

    • Description

    • Synthetic 24-mer peptide derived from LL-37 for binding to lipopolysaccharides or lipoteichoic acid

    • Activity

    • Antibacterial

    • Target Organism

      • No MICs found on DRAMP database

    • Reference

      • Not available

Clinical Information

    • Medical use

    • Chronic suppurative otitis media (middle ear infections)

    • Company

    • OctoPlus BV, Dr Reddy’s Research and Development BV

    • Stage of Development

    • Phase II (Completed)

    • Comments

    • Clinical proof-of-efficacy in Phase II trials; no Phase III trials proposed yet.

    • Clinical Trials

    • ISRCTN12149720