Sequence Information

    • DRAMP ID

    • DRAMP18164

    • Name

    • AP-214(Modimelanotide)

    • Sequence

    • KKKKKKSYSMEHFRWGKPV

    • Description

    • Synthetic derivative from HDP α-melanocyte-stimulating hormone

    • Activity

    • Antibacterial

    • Target Organism

      • No MICs found on DRAMP database

    • Reference

      • AP214, an analogue of alpha-melanocyte-stimulating hormone, ameliorates sepsis-induced acute kidney injury and mortality.(PMID: 18354376)

Clinical Information

    • Medical use

    • ①Prevention of acute kidney injury after cardiac surgery; ②Treatment of sepsis.

    • Company

    • Action Pharma A/S (Aarhus and Copenhagen, Denmark)

    • Stage of Development

    • Phase II (Completed)

    • Comments

    • No more comments

    • Clinical Trials

    • NCT01256372
    • NCT00903604
    • NCT00628264