Sequence Information

    • DRAMP ID

    • DRAMP18178

    • Name

    • IDR-1

    • Sequence

    • KSRIVPAIPVSLL

    • Description

    • IDR-1 is a 13-amino acid peptide derived from bovine neutrophils that shows antimicrobial activity against MRSA, VRE, and other Gram-positive and Gram-negative pathogens.

    • Activity

    • Chemokine induction and reduction of pro-inflammatory cytokines (Scott et al., 2007)

    • Target Organism

      • No MICs found on DRAMP database

    • Reference

      • An anti-infective peptide that selectively modulates the innate immune response. Nat Biotechnol (2007)(PMID: 17384586)

Clinical Information

    • Medical use

    • Prevention of infections in the immune compromised

    • Company

    • Unknown

    • Stage of Development

    • Phase I

    • Comments

    • Immunomodulation, protection of }monocytes

    • Clinical Trials