• • DRAMP ID

  • DRAMP00766

• • Peptide Name

  • JCpep7 (Plants)

• • Source

  • Jatropha curcas

• • Family

  • Not found

• • Gene

  • Not found

• • Sequence

  • KVFLGLK

• • Sequence Length

  • 7

• • UniProt Entry

  • No entry found

• • Protein Existence

  • Not found

• • Biological Activity

  • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-

• • Target Organism

  • • Gram-negative bacteria: Salmonella typhimurium ATCC 50013 (MIC=48 µg/ml), Shigella dysenteriae ATCC 51302 (MIC=48 µg/ml), Pseudomonas aeruginosa ATCC 27553 (MIC=64 µg/ml);
    • Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=40 µg/ml), Bacillus subtilis ATCC 23631 (MIC=24 µg/ml), Streptococcus pneumoniae ATCC 49619 (MIC=56 µg/ml).

• • Hemolytic Activity

  • • No hemolysis information or data found in the reference(s) presented in this entry

• • Cytotoxicity

  • No cytotoxicity information found in the reference(s) presented

• • Binding Target

  • Not found

• • Linear/Cyclic

  • Linear

• • N-terminal Modification

  • Free

• • C-terminal Modification

  • Free

• • Nonterminal Modifications and Unusual Amino Acids

  • None

• • Stereochemistry

  • L

• • Structure

  • Not found

• • Structure Description

  • Not found

• • Helical Wheel Diagram

  • 

• • PDB ID

  • None

• Predicted Structure

• There is no predicted structure for DRAMP00766.

DRAMP00766

• • Function

  • JCpep7 killed microbes principally via breaking of their cell walls and membranes, followed by cell lysis.

• ·Literature 1

• • Title

  • Efficient Screening of a Novel Antimicrobial Peptide from Jatropha curcas by Cell Membrane Affinity Chromatography.

• • Pubmed ID

  • 21268582

• • Reference

  • J Agric Food Chem. 2011 Feb 23;59(4):1145-1151.

• • Author

  • Xiao J, Zhang H, Niu L, Wang X.