General Information

    • DRAMP ID

    • DRAMP01092

    • Peptide Name

    • Alytesin (toads, amphibians, animals)

    • Source

    • Alytes obstetricans (Common midwife toad) (Bufo obstetricans)

    • Family

    • Belongs to the bombesin/neuromedin-B/ranatensin family

    • Gene

    • Not found

    • Sequence

    • QGRLGTQWAVGHLM

    • Sequence Length

    • 14

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Unknown

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP01092 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP01092.

Physicochemical Information

    • Formula

    • C68H108N22O18S

    • Absent Amino Acids

    • CDEFIKNPSY

    • Common Amino Acids

    • G

    • Mass

    • 1553.8

    • PI

    • 9.76

    • Basic Residues

    • 2

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 5

    • Net Charge

    • +2

    • Boman Index

    • -10.04

    • Hydrophobicity

    • -0.143

    • Aliphatic Index

    • 83.57

    • Half Life

      • Mammalian:0.8 hour
      • Yeast:10 min
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 5500

    • Absorbance 280nm

    • 423.08

    • Polar Residues

    • 4

DRAMP01092

Comments Information

    • Function

    • Amphibian defensive peptide.

    • Tissue specificity

    • Expressed by the skin glands.

Literature Information

  • ·Literature 1

    • Title

    • Active peptides in the skins of one hundred amphibian species from Australia and Papua New Guinea.

    • Reference

    • Comp Biochem Physiol C. 1984;77(1):99-108.

    • Author

    • Erspamer V, Erspamer GF, Mazzanti G, Endean R.