• • DRAMP ID

  • DRAMP01188

• • Peptide Name

  • Chensinin-1ZHa (Frogs, amphibians, animals)

• • Source

  • Rana zhenhaiensis (Chinese brown frog)

• • Family

  • Not found

• • Gene

  • Not found

• • Sequence

  • LALKSGGWLRLFGLKDKKH

• • Sequence Length

  • 19

• • UniProt Entry

  • No entry found

• • Protein Existence

  • Not found

• • Biological Activity

  • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal

• • Target Organism

  • • Gram-positive bacterium: Staphylococcus aureus ATCC 2592 (MIC=17 µM);
    • Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=35 µM), Pseudomonas aeruginosa ATCC 9027 (MIC=9 µM).
    • Yeast: Candida albicans ATCC 2002 (MIC=35 µM).

• • Hemolytic Activity

  • • No hemolysis information or data found in the reference(s) presented in this entry

• • Cytotoxicity

  • No cytotoxicity information found in the reference(s) presented

• • Binding Target

  • Not found

• • Linear/Cyclic

  • Linear

• • N-terminal Modification

  • Free

• • C-terminal Modification

  • Amidation

• • Nonterminal Modifications and Unusual Amino Acids

  • Free

• • Stereochemistry

  • L

• • Structure

  • Not found

• • Structure Description

  • Not found

• • Helical Wheel Diagram

  • 

• • PDB ID

  • None

• Predicted Structure

• Please click DRAMP01188_predicted_structure.pdb to download.

DRAMP01188

• • Comment

  • No comments found on DRAMP database

• ·Literature 1

• • Title

  • Molecular Cloning and Functional Characterization of Novel Antimicrobial Peptides from the Skin of Brown Frog, Rana zhenhaiensis.

• • Pubmed ID

  • 22943778

• • Reference

  • Zoolog Sci. 2012 Sep;29(9):553-558.

• • Author

  • Xu B, Che H, Kang L, Zheng S, Mu S, Wan F.