• • DRAMP ID

  • DRAMP01391

• • Peptide Name

  • Odorranain-U1 (OdU1; Frogs, amphibians, animals)

• • Source

  • Odorrana grahami (Yunnanfu frog) (Rana grahami)

• • Family

  • Not found

• • Gene

  • Not found

• • Sequence

  • GCSRWIIGIHGQICRD

• • Sequence Length

  • 16

• • UniProt Entry

  • A6MBS4

• • Protein Existence

  • Transcript level

• • Biological Activity

  • Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-

• • Target Organism

  • • [Ref.17272268] Gram-negative bacterium: Escherichia coli (MIC>100 μg/ml);
    • Gram-positive bacteria: Staphylococcus aureus (MIC=75.00 μg/ml), Bacillus subtilis (MIC=9.37 μg/ml).
    • Yeast: Candida albicans (MIC=9.37 μg/ml).

• • Hemolytic Activity

  • • No hemolysis information or data found in the reference(s) presented in this entry

• • Cytotoxicity

  • • Not included yet

• • Binding Target

  • Not found

• • Linear/Cyclic

  • Not included yet

• • N-terminal Modification

  • Not included yet

• • C-terminal Modification

  • Not included yet

• • Nonterminal Modifications and Unusual Amino Acids

  • Not included yet

• • Stereochemistry

  • Not included yet

• • Structure

  • Not found

• • Structure Description

  • Odorranain-U1 adopts 60.2%

• • Helical Wheel Diagram

  • 

• • PDB ID

  • None

• Predicted Structure

• There is no predicted structure for DRAMP01391.

DRAMP01391

• • Function

  • Odorranain-U1 exhibites moderate antimicrobial activities against all of the tested microbes.

• ·Literature 1

• • Title

  • Anti-infection peptidomics of amphibian skin.

• • Pubmed ID

  • 17272268

• • Reference

  • Mol Cell Proteomics. 2007 May;6(5):882-894.

• • Author

  • Li J, Xu X, Xu C, Zhou W, Zhang K, Yu H, Zhang Y, Zheng Y, Rees HH, Lai R, Yang D, Wu J.