• • DRAMP ID

  • DRAMP01765

• • Peptide Name

  • Temporin-1TGb (Frogs, amphibians, animals)

• • Source

  • Rana tagoi (Tago frog)

• • Family

  • Belongs to the frog skin active peptide family (Brevinin subfamily)

• • Gene

  • tmpTGb

• • Sequence

  • AVDLAKIANKVLSSLF

• • Sequence Length

  • 16

• • UniProt Entry

  • Q2PGA7

• • Protein Existence

  • Homology

• • SMILES

  • CC[C@@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H](NC(=O)[C@H](C)N)C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(N)=O)C(C)C

• • Biological Activity

  • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-

• • Target Organism

  • • Gram-positive bacterium:

      Target Organism	Activity
      Staphylococcus aureus (MIC>150 µM);	-

    • Gram-negative bacterium:

      Target Organism	Activity
      Escherichia coli	MIC=37.5 µM

• • Hemolytic Activity

  • • No hemolysis information or data found in the reference(s) presented in this entry

• • Cytotoxicity

  • No cytotoxicity information found in the reference(s) presented

• • Binding Target

  • Not found

• • Linear/Cyclic

  • Linear

• • N-terminal Modification

  • Free

• • C-terminal Modification

  • Amidation

• • Nonterminal Modifications and Unusual Amino Acids

  • Free

• • Stereochemistry

  • L

• • Structure

  • Not found

• • Structure Description

  • Not found

• • PDB ID

• Predicted Structure

• There is no predicted structure for DRAMP01765.

DRAMP01765

• • Comment

  • No comments found on DRAMP database

• ·Literature 1

• • Title

  • Molecular cloning and sequence analyses of preprotemporin mRNAs containing premature stop codons from extradermal tissues of Rana tagoi.

• • Pubmed ID

  • 16675060

• • Reference

  • Peptides. 2006 Sep;27(9):2124-2128.

• • Author

  • Iwamuro S, Nakamura M, Ohnuma A, Conlon JM.