• • DRAMP ID

  • DRAMP02378

• • Peptide Name

  • Grammistin Gs A (Group III grammistin; soapfish, chordates, animals)

• • Source

  • Grammistes sexlineatus (Sixline soapfish) (Golden stripe soapfish)

• • Family

  • Belongs to the grammistin family (Group 3 subfamily)

• • Gene

  • Not found

• • Sequence

  • WWRELLKKLAFTAAGHLGSVLAAKQSGW

• • Sequence Length

  • 28

• • UniProt Entry

  • P69845

• • Protein Existence

  • Protein level

• • Biological Activity

  • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-

• • Target Organism

  • • Gram-positive bacteria: Bacillus subtilis IAM 1026 (MIC=25 µg/ml), Staphylococcus aureus IAM 1011 (MIC=12.5 µg/ml);
    • Gram-negative bacteria: Aeromonas salmonicida NCIBM 1102 (MIC=25 µg/ml), Escherichia coli JCM 1649 (MIC=50 µg/ml), P. dameselae subsp. Piscicida Sp 9587 (MIC=25 µg/ml), Salmonella typhimurium S1 (MIC>50 µg/ml), S. putrefaciens IAM 1509 (MIC=6.25 µg/ml), Vibrio anguillarum NCIBM 829 (MIC=50 µg/ml), Vibrio parahaemolyticus (MIC=50 µg/ml).

• • Hemolytic Activity

  • • No hemolysis information or data found in the reference(s) presented in this entry

• • Cytotoxicity

  • • Not included yet

• • Binding Target

  • Not found

• • Linear/Cyclic

  • Not included yet

• • N-terminal Modification

  • Not included yet

• • C-terminal Modification

  • Not included yet

• • Nonterminal Modifications and Unusual Amino Acids

  • Not included yet

• • Stereochemistry

  • Not included yet

• • Structure

  • Not found

• • Structure Description

  • Not found

• • Helical Wheel Diagram

  • 

• • PDB ID

  • None

• Predicted Structure

• There is no predicted structure for DRAMP02378.

DRAMP02378

• • Comment

  • No comments found on DRAMP database

• ·Literature 1

• • Title

  • Further isolation and characterization of grammistins from the skin secretion of the soapfish Grammistes sexlineatus.

• • Pubmed ID

  • 15777955

• • Reference

  • Toxicon. 2005 Apr;45(5):595-601.

• • Author

  • Sugiyama N, Araki M, Ishida M, Nagashima Y, Shiomi K.