General Information

    • DRAMP ID

    • DRAMP02763

    • Peptide Name

    • Ponericin-W2 (ants, insects, animals)

    • Source

    • Pachycondyla goeldii (Ponerine ant)

    • Family

    • Belongs to the ponericin-W family

    • Gene

    • Not found

    • Sequence

    • WLGSALKIGAKLLPSVVGLFQKKKK

    • Sequence Length

    • 25

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Antibacterial, Antifungal, Insecticidal, Antimicrobial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP02763 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP02763.

Physicochemical Information

    • Formula

    • C130H221N33O29

    • Absent Amino Acids

    • CDEHMNRTY

    • Common Amino Acids

    • K

    • Mass

    • 2710.39

    • PI

    • 10.7

    • Basic Residues

    • 6

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 12

    • Net Charge

    • +6

    • Boman Index

    • 3.71

    • Hydrophobicity

    • 0.244

    • Aliphatic Index

    • 124.8

    • Half Life

      • Mammalian:2.8 hour
      • Yeast:3 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 5500

    • Absorbance 280nm

    • 229.17

    • Polar Residues

    • 5

DRAMP02763

DRAMP02763 chydropathy plot

Comments Information

    • Function

    • Broad spectrum of activity against both Gram-positive and Gram-negative bacteria. Has insecticidal activities.

    • Tissue specificity

    • Expressed by the venom gland.

Literature Information

  • ·Literature 1

    • Title

    • Ponericins, new antibacterial and insecticidal peptides from the venom of the ant Pachycondyla goeldii.

    • Reference

    • J. Biol. Chem. 2001; 276: 17823-17829.

    • Author

    • Orivel J, Redeker V, Le Caer JP, Krier F, Revol-Junelles AM, Longeon A, Chaffotte A, Dejean A, Rossier J.