General Information
-
DRAMP ID
- DRAMP02931
-
Peptide Name
- Arasin-likeSp (crabs, Arthropods, animals)
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Source
- Scylla paramamosain (Mud crab)
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Family
- Not found
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Gene
- Not found
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Sequence
- SPRVSRRYGRPFGGRPFVGGQFGGRPGCVCIRSPCPCANYG
-
Sequence Length
- 41
-
UniProt Entry
- No entry found
-
Protein Existence
- Not found
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
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Target Organism
-
- Gram-positive bacteria:
Target Organism Activity Staphylococcus haemolyticus MIC=6.25-12.5 µM Aerococcus viridans MIC=0.19-0.39 µM Micrococcus luteus MIC=0.39-0.78 µM Bacillus subtilis (MIC=6.25-12.5 µM); - - Gram-negative bacteria:
Target Organism Activity Escherichia coli 363 MIC>50 µM Aeromonas hydrophila MIC>50 µM V. harveyi MIC=0.78-1.56 µM Vibrio anguillarum MIC=3.125-6.25 µM
- Gram-positive bacteria:
-
Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
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Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
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N-terminal Modification
- Not included yet
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C-terminal Modification
- Not included yet
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Nonterminal Modifications and Unusual Amino Acids
- Not included yet
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Stereochemistry
- Not included yet
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Structure
- Not found
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Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
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Predicted Structure
- There is no predicted structure for DRAMP02931.
Physicochemical Information
-
Formula
- C189H292N64O49S4
Absent Amino Acids
- DEHKLMTW
Common Amino Acids
- G
Mass
- 4373.04
PI
- 10.75
Basic Residues
- 7
Acidic Residues
- 0
Hydrophobic Residues
- 8
Net Charge
- +7
-
Boman Index
- -85.73
Hydrophobicity
- -0.473
Aliphatic Index
- 33.17
Half Life
-
- Mammalian:1.9 hour
- Yeast:>20 hour
- E.coli:>10 hour
Extinction Coefficient Cystines
- 3230
Absorbance 280nm
- 80.75
Polar Residues
- 19
DRAMP02931
Comments Information
Comment
- No comments found on DRAMP database
Literature Information
- ·Literature 1
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Title
- Two novel antimicrobial peptides, arasin-likeSp and GRPSp, from the mud crab Scylla paramamosain, exhibit the activity against some crustacean pathogenic bacteria.
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Pubmed ID
- 21220028
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Reference
- Fish Shellfish Immunol. 2011 Feb;30(2):706-712.
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Author
- Imjongjirak C, Amparyup P, Tassanakajon A.
