General Information
-
DRAMP ID
- DRAMP03004
-
Peptide Name
- Abaecin (Insects, animals)
-
Source
- Bombus pascuorum (Brown bumblebee)
-
Family
- Not found
-
Gene
- Not found
-
Sequence
- FVPYNPPRPGQSKPFPSFPGHGPFNPKIQWPYPLPNPGH
-
Sequence Length
- 39
-
UniProt Entry
- P81463
-
Protein Existence
- Protein level
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial, Anti-Gram-
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Target Organism
-
- Gram-negative bacteria: Micrococcus luteus;
- Gram-negative bacteria: Escherichia coli D22.
-
Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
-
Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Not found
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP03004.
Physicochemical Information
-
Formula
- C213H294N54O49
Absent Amino Acids
- ACDEMT
Common Amino Acids
- P
Mass
- 4395.01
PI
- 10
Basic Residues
- 5
Acidic Residues
- 0
Hydrophobic Residues
- 8
Net Charge
- +5
-
Boman Index
- -41.53
Hydrophobicity
- -1.026
Aliphatic Index
- 27.44
Half Life
-
- Mammalian:1.1 hour
- Yeast:3 min
- E.coli:2 min
Extinction Coefficient Cystines
- 8480
Absorbance 280nm
- 223.16
Polar Residues
- 11
DRAMP03004
Comments Information
Function
- Antibacterial peptide against Gram-positive and Gram-negative bacteria.
Induction
- By bacterial infection.
Literature Information
- ·Literature 1
-
Title
- Novel antibacterial peptides isolated from a European bumblebee, Bombus pascuorum (Hymenoptera, Apoidea).
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Pubmed ID
- 9219367
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Reference
- Insect Biochem Mol Biol. 1997 May;27(5):413-22.
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Author
- Rees JA, Moniatte M, Bulet P.