• • DRAMP ID

  • DRAMP20783

• • Peptide Name

  • Pleurain-M1 (Frogs,amphibians,animals)

• • Source

  • Nidirana pleuraden (Yunnan pond frog)

• • Family

  • Belongs to the frog skin active peptide (FSAP) family. Pleurain subfamily.

• • Gene

  • Not found

• • Sequence

  • GLLDSVKEGLKKVAGQLLDTLKCKISGCTPA

• • Sequence Length

  • 31

• • UniProt Entry

  • B5L1L3

• • Protein Existence

  • Not found

• • Biological Activity

  • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-

• • Target Organism

  • • [Ref.19028675] Gram-negative bacteria: Escherichia coli (MIC=6.3 μg/ml);
    • Gram-positive bacteria: Staphylococcus aureus (MIC=6.3 μg/ml), Bacillus subtilis (MIC=25 μg/ml);
    • Yeast: Candida albicans(MIC=12.5 μg/ml).

• • Hemolytic Activity

  • • No hemolysis information or data found in the reference(s) presented in this entry

• • Cytotoxicity

  • No cytotoxicity information found in the reference(s) presented

• • Binding Target

  • Not found

• • Linear/Cyclic

  • Linear

• • N-terminal Modification

  • Free

• • C-terminal Modification

  • Free

• • Nonterminal Modifications and Unusual Amino Acids

  • None

• • Stereochemistry

  • L

• • Structure

  • Not found

• • Structure Description

  • Not found

• • Helical Wheel Diagram

  • 

• • PDB ID

  • None

• Predicted Structure

• There is no predicted structure for DRAMP20783.

DRAMP20783

• • Function

  • Antimicrobial activity against Gram-positive bacteria, Gram-negative bacteria and fungi.

• ·Literature 1

• • Title

  • Antioxidant peptidomics reveals novel skin antioxidant system.

• • Pubmed ID

  • 19028675

• • Reference

  • Mol Cell Proteomics. 2009 Mar;8(3):571-83.

• • Author

  • Yang H, Wang X, Liu X, Wu J, Liu C, Gong W, Zhao Z, Hong J, Lin D, Wang Y, Lai R.