Patent Information

    • DRAMP ID

    • DRAMP04862

    • Sequence

    • KKWWRRALQALKNGPALSNV

    • Sequence Length

    • 20

    • Sequence Name

    • Sequence 17 from Patent US 20030176337

    • Source

    • Synthetic construct

    • Activity

    • Antimicrobial, Antibacterial

    • Patent Type

    • Patent Application

    • Publication Date

    • 2003-9-18

    • Patent Title

    • Antimicrobial cationic peptides.

    • Abstract

    • A novel class of cationic peptides having antimicrobial activity is provided. Examples of such peptides include NH2-KWKSFIKKLTTAVKKVLTTGLPALIS-COOH (SEQ ID NO: 1) and NH2-KWKSFIKKLTSAAKKVVTTAKPLISS-COOH (SEQ ID NO: 2). Also provided are methods for inhibiting the growth of bacteria utilizing the peptides of the invention. The peptides are particularly useful for inhibiting endotoxemia in a subject.