Patent Information

    • DRAMP ID

    • DRAMP29826

    • Sequence

    • MFFNFMKKVDVKKNFGYKEVSRKDLAKVNGGKRKKHRCRVYNNGMPTGMYRWC

    • Sequence Length

    • 53

    • Sequence Name

    • Sequence 264 from US 20230416797

    • Source

    • Lactobacillus salivarius

    • Activity

    • Antimicrobial

    • Patent Type

    • Patent Application

    • Publication Date

    • 2023-12-28

    • Patent Title

    • MODULATING ANTIMICROBIAL PEPTIDE HALF-LIFE

    • Abstract

    • Methods of modulating the half-life of an antimicrobial peptide are described. The method may include administering an antimicrobial peptide to an environment where the antimicrobial peptide remains active until a specified endpoint, and on or after the specified endpoint, digesting the antimicrobial peptide with a protease to thereby inactivate the antimicrobial peptide and modulate its half-life. Compositions and kits for modulating the half-life of an antimicrobial peptide are also described.