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Sequence Name
- Sequence 270 from US 20230416797
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Source
- Synthetic construct
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Patent Type
- Patent Application
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Publication Date
- 2023-12-28
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Patent Title
- MODULATING ANTIMICROBIAL PEPTIDE HALF-LIFE
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Abstract
- Methods of modulating the half-life of an antimicrobial peptide are described. The method may include administering an antimicrobial peptide to an environment where the antimicrobial peptide remains active until a specified endpoint, and on or after the specified endpoint, digesting the antimicrobial peptide with a protease to thereby inactivate the antimicrobial peptide and modulate its half-life. Compositions and kits for modulating the half-life of an antimicrobial peptide are also described.