Patent Information

    • DRAMP ID

    • DRAMP32391

    • Sequence

    • GNKKWEQKQVQIKTLEGEFSVTMWSS

    • Sequence Length

    • 26

    • Sequence Name

    • OPB

    • Source

    • YY1 protein

    • Activity

    • Antimicrobial, Anticancer

    • Patent Type

    • Granted Patent

    • Publication Date

    • 2019-6-7

    • Patent Title

    • Anticancer active OPB (oligopeptidase B) oligopeptide and expression vector and application thereof

    • Abstract

    • A kind of OPB oligopeptides and its expression vector and application with anticancer activity, it is related to a kind of oligopeptides with anticancer activity and its expression vector and application.Sequence of the invention is Gly-Asn-Lys-Lys-Trp-Glu-Gln-Lys-Gln-Val-Gln-Ile-Lys-Thr- Leu-Glu-Gly-Glu-Phe-Ser-Val-Thr-Met-Trp-Ser-Ser.It is used to prepare anticancer drug.The present invention constructs pMBP-2xOPB expression vector.The present invention has the effect of that inhibition growth of tumour cell is proliferated using the peptide fragment that OPB sequent synthesis goes out, and shows that peptide fragment and its derivative based on OPB are a kind of drugs of potential treating cancer.