Patent Information

    • DRAMP ID

    • DRAMP36175

    • Sequence

    • CVKRGLKLRHVRPRVTRDV

    • Sequence Length

    • 19

    • Sequence Name

    • DPV1048

    • Source

    • Protein derived

    • Activity

    • Antimicrobial, Anticancer

    • Patent Type

    • Granted Patent

    • Publication Date

    • 2009-7-23

    • Patent Title

    • Cell Penetrating Peptide Conjugates for Delivering of Nucleic Acids into a Cell

    • Abstract

    • The invention provides cell penetrating peptide-nucleic acid conjugates having the formula P-L-N, wherein P is a cell penetrating peptide, N is a nucleic acid, preferably an oligonucleotide and more preferably a siRNA, and L is a hydrophilic polymer, preferably a polyethylene glycol (PEG)-based linker linking P and N together. Compositions, methods of use and methods for producing such conjugates are also disclosed.