Patent Information

    • DRAMP ID

    • DRAMP36192

    • Sequence

    • GLWRALWRALWRSLWKLKWKV

    • Sequence Length

    • 21

    • Sequence Name

    • CADY-2 (SEQ ID No: 8)

    • Source

    • Synthetic

    • Activity

    • Antimicrobial, Anticancer

    • Patent Type

    • Granted Patent

    • Publication Date

    • 2011-5-17

    • Patent Title

    • Cell penetrating peptides for intracellular delivery of molecules

    • Abstract

    • The present invention concerns cell-penetrating peptides which comprise an amino acid sequence consisting of GLX9WRAX9WRX1LX2RSLX9WX3X4X5X6X7X8(SEQ ID No: 1), wherein X1 is A, L or G, X2 is W or none, X3 is R or K, X4 is K, L or S, X5 is L or K, X6 is R or W, X7 is K or S, and X8 is A, V or Q, and X9 is W, F or Y. These CPPs can be used as vectors for delivering nucleic acids and/or proteins and/or peptides to cells, in vitro or in vivo.