• DRAMP ID

    • DRAMP29845
    • Peptide Name

    • Lfc8
    • Source

    • Synthetic construct
    • Family

    • Not found
    • Gene

    • Not found
    • Sequence

    • RRWQWRMKKLG
    • Sequence Length

    • 11
    • UniProt Entry

    • No entry found
    • Protein Existence

    • Not found
    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
    • Target Organism

      • Gram-negative bacterium: Escherichia coli(LD99=3.8 µM);
      • Gram-positive bacteria: Staphylococcus aureus(LD99=15 µM), Bacillus subtilis(LD99≦0.45 µM).
    • Hemolytic Activity

      • None of the peptides are hemolytic
    • Cytotoxicity

    • No cytotoxicity information found in the reference(s) presented
    • Binding Target

    • Not found
    • Serum or Protease Type

    • Human Serum
    • Stability Data

    • Have half-lives of ∼1.5 h.
    • Assay

    • RP-HPLC
    • Linear/Cyclic

    • Cyclic
    • N-terminal Modification

    • Cyclization (N termini to C termini)
    • C-terminal Modification

    • Cyclization (C termini to N termini)
    • Nonterminal Modifications and Unusual Amino Acids

    • Free
    • Stereochemistry

    • L
    • Structure

    • Not found
    • Structure Description

    • Not found
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP29845.
  • ·Literature 1
    • Title

    • Serum stabilities of short tryptophan- and arginine-rich antimicrobial peptide analogs.
    • Reference

    • PLoS One. 2010 Sep 10;5(9):e12684.
    • Author

    • Nguyen LT, Chau JK, Perry NA, de Boer L, Zaat SA, Vogel HJ.