• DRAMP ID

    • DRAMP00019
    • Peptide Name

    • SmbA2 (Bacteriocin)
    • Source

    • Streptococcus mutans GS5 (Gram-negative bacteria)
    • Family

    • Belongs to the lantibiotic family (Class I bacteriocin)
    • Gene

    • Unknow
    • Sequence

    • STPACAIGVVGITVAVTGISTACTSRCINK
    • Sequence Length

    • 30
    • Swiss_Prot Entry

    • No entry found
    • Evidence code

    • Unknow
    • Biological Activity

    • Antibacterial
    • Target Organism

      • No MICs found on DRAMP database
    • Binding Traget

    • Unknow
    • Structure

    • Unknow
    • Structure Description

    • Unknow
    • PDB ID

    • Unknow
    • DRAMP00019 helical wheel diagram
    • Formula

    • C121H213N35O40S3
    • Absent Amino Acids

    • DEFHLMQWY
    • Common Amino Acids

    • T
    • Mass

    • 3411.88
    • PI

    • 8.52
    • Basic Residues

    • 2
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 12
    • Boman Index

    • -0.42
    • Hydrophobicity

    • 96.33
    • Aliphatic Index

    • 104
    • Half Life

      • Mammalian:1.9 hour
      • Yeast:>20 hour
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 125
    • Absorbance 280nm

    • 4.31
    • Polar Residues

    • 15
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Amino Acid Distribution

DRAMP00019 chydropathy plot
    • The two peptides (SmbA and SmbB) are encoded by two chromosomal DNA genes in the same operon.

  • Literature 1
    • Reference

    • Antimicrob Agents Chemother. 2005 Feb;49(2):541-548.
    • Author

    • Yonezawa H, Kuramitsu HK.
    • Title

    • Genetic analysis of a unique bacteriocin, Smb, produced by Streptococcus mutans GS5.