General Information

    • DRAMP ID

    • DRAMP00065

    • Peptide Name

    • Plantaricin 1.25 beta (thermostable Bacteriocin)

    • Source

    • Lactobacillus plantarum TMW1.25 (Gram-positive bacteria)

    • Family

    • Belongs to the class II bacteriocin

    • Gene

    • plnB

    • Sequence

    • KKKKKKVACTWGNAATAAASGAVXGILGGPTGALAGAIWGVSQCASNNLHGMH

    • Sequence Length

    • 53

    • Protein Existence

    • Predicted

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • Plantarum, Plantarum sp, Plantarum coryniformis.

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP00065 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP00065.

Physicochemical Information

    • Formula

    • C220H358N68O62S3

    • Absent Amino Acids

    • DEFRY

    • Common Amino Acids

    • A

    • Mass

    • 5173.21

    • PI

    • 10.05

    • Basic Residues

    • 8

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 21

    • Net Charge

    • +8

    • Boman Index

    • -11.33

    • Hydrophobicity

    • 0.083

    • Aliphatic Index

    • 73.96

    • Half Life

      • Mammalian:1.3 hour
      • Yeast:3 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 11125

    • Absorbance 280nm

    • 213.94

    • Polar Residues

    • 20

DRAMP00065

DRAMP00065 chydropathy plot

Comments Information

    • Lactobacillus plantarum TMW1.25 produces two bacteriocins plantaricin 1.25a and plantaricin 1.25b.

Literature Information

  • ·Literature 1

    • Title

    • A gene cluster encoding plantaricin 1.25beta and other bacteriocin-like peptides in Lactobacillus plantarum TMW1.25.

    • Reference

    • Biochim Biophys Acta. 2000 Feb 29;1490(3):355-361.

    • Author

    • Ehrmann MA, Remiger A, Eijsink VG, Vogel RF.