General Information

    • DRAMP ID

    • DRAMP00083

    • Peptide Name

    • Bavaricin-A (Bacteriocin)

    • Source

    • Lactobacillus sakeii (Gram-positive bacteria)

    • Family

    • Belongs to the class IIa bacteriocin

    • Gene

    • Not found

    • Sequence

    • KYYGNGVHXGKHSXTVDWGTAIGNIGNNAAANXATGXNAGG

    • Sequence Length

    • 41

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+

    • Target Organism

      • Gram-positive bacteria: Lactobacillus, Listeria monocytogenes, Pediococcus, Enterococcus, Leuconostoc, Lactococcus.

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP00083 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

Physicochemical Information

    • Formula

    • C154H224N50O48

    • Absent Amino Acids

    • CEFLMPQR

    • Common Amino Acids

    • G

    • Mass

    • 4061.16

    • PI

    • 8.45

    • Basic Residues

    • 4

    • Acidic Residues

    • 1

    • Hydrophobic Residues

    • 11

    • Net Charge

    • +3

    • Boman Index

    • -40.8

    • Hydrophobicity

    • -0.5

    • Aliphatic Index

    • 47.8

    • Half Life

      • Mammalian:1.3 hour
      • Yeast:3 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 8480

    • Absorbance 280nm

    • 212

    • Polar Residues

    • 21

DRAMP00083

DRAMP00083 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Antimicrobial activity of lactic acid bacteria isolated from sour doughs: purification and characterization of bavaricin A, a bacteriocin produced by Lactobacillus bavaricus MI401.

    • Reference

    • J Appl Bacteriol. 1993 Aug;75(2):113-122.

    • Author

    • Larsen AG, Vogensen FK, Josephsen J.