General Information

    • DRAMP ID

    • DRAMP00084

    • Peptide Name

    • Mutacin F-59.1 (Bacteriocin)

    • Source

    • Streptococcus mutans (Gram-positive bacteria)

    • Family

    • Belongs to the class IIa bacteriocin

    • Gene

    • Not found

    • Sequence

    • KYYGNGVTCGKHSXSVDWXKXT

    • Sequence Length

    • 22

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP00084 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP00084.

Physicochemical Information

    • Formula

    • C94H134N26O26S

    • Absent Amino Acids

    • AEFILMPQR

    • Common Amino Acids

    • GKX

    • Mass

    • 2464.35

    • PI

    • 9.05

    • Basic Residues

    • 4

    • Acidic Residues

    • 1

    • Hydrophobic Residues

    • 3

    • Net Charge

    • +3

    • Boman Index

    • -34.38

    • Hydrophobicity

    • -0.85

    • Aliphatic Index

    • 26.36

    • Half Life

      • Mammalian:1.3 hour
      • Yeast:3 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 8480

    • Absorbance 280nm

    • 403.81

    • Polar Residues

    • 11

DRAMP00084

DRAMP00084 chydropathy plot

Comments Information

    • Function

    • Bactericidal activity (By similarity).

Literature Information

  • ·Literature 1

    • Title

    • Characterization of mutacin F-59.1, a pediocin-like bacteriocin produced by Streptococcus mutans 59.1.

    • Reference

    • Submitted (OCT-2009) to UniProtKB

    • Author

    • Nicolas GG, Lavoie MC, Lapointe G, Mota-Meira M.