General Information

    • DRAMP ID

    • DRAMP00088

    • Peptide Name

    • Enterocin-HF (Bacteriocin)

    • Source

    • Enterococcus faecium (Streptococcus faecium) (Gram-positive bacteria)

    • Family

    • Belongs to the class IIa bacteriocin

    • Gene

    • Not found

    • Sequence

    • KYYGNGVSCNKKGCSVDWGKAIGIIGNNAAANLTTGGKAAWAC

    • Sequence Length

    • 43

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP00088 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP00088.

Physicochemical Information

    • Formula

    • C188H295N55O57S3

    • Absent Amino Acids

    • EFHMPQR

    • Common Amino Acids

    • G

    • Mass

    • 4333.92

    • PI

    • 9.26

    • Basic Residues

    • 5

    • Acidic Residues

    • 1

    • Hydrophobic Residues

    • 15

    • Net Charge

    • +4

    • Boman Index

    • -25.44

    • Hydrophobicity

    • -0.123

    • Aliphatic Index

    • 66.05

    • Half Life

      • Mammalian:1.3 hour
      • Yeast:3 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 14105

    • Absorbance 280nm

    • 335.83

    • Polar Residues

    • 22

DRAMP00088

DRAMP00088 chydropathy plot

Comments Information

    • Function

    • Bacteriocin.

    • PTM

    • Contains one disulfide bond 9-14.

Literature Information

  • ·Literature 1

    • Title

    • Amino acid sequence of Enterocin-HF, a new pediocin-like bacteriocin produced by E. faecium HS and E. faecium TA29 isolated from humans and fish (thin-lipped grey mullet; Liza ramada) in Portugal.

    • Reference

    • Submitted (JAN-2009) to UniProtKB.

    • Author

    • Almeida T, Brandao A, Campanero C, Igrejas G, Torres C, Herandez P.E, Poeta P, Cintas L.M, Herranz C.