• DRAMP ID

    • DRAMP00099
    • Peptide Name

    • Sakacin 5X (Sak5X; Pediocin-like peptide; Bacteriocin)
    • Source

    • lactic acid bacteria (Gram-positive bacteria)
    • Family

    • Belongs to the class IIa bacteriocin
    • Gene

    • Not found
    • Sequence

    • KYYGNGLSCNKSGCSVDWSKAISIIGNNAVANLTTGGAAGWKS
    • Sequence Length

    • 43
    • UniProt Entry

    • No entry found
    • Protein Existence

    • Not found
    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+
    • Target Organism

      • Gram-positive bacteria: Lactobacillus lactis 105, L. collinoides 110, L. brevis 111, L. brevis 112, Pediococcus damnosus 113, P. damnosus 114, Enterococcus faecalis 109.
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Bridge
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP00099 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP00099.
    • Formula

    • C189H296N54O61S2
    • Absent Amino Acids

    • EFHMPQR
    • Common Amino Acids

    • G
    • Mass

    • 4364.87
    • PI

    • 9.19
    • Basic Residues

    • 4
    • Acidic Residues

    • 1
    • Hydrophobic Residues

    • 14
    • Net Charge

    • +3
    • Boman Index

    • -34.41
    • Hydrophobicity

    • -0.151
    • Aliphatic Index

    • 70.47
    • Half Life

      • Mammalian:1.3 hour
      • Yeast:3 min
      • E.coli:2 min
    • Extinction Coefficient Cystines

    • 14105
    • Absorbance 280nm

    • 335.83
    • Polar Residues

    • 24

DRAMP00099

DRAMP00099 chydropathy plot
    • Comment

    • No comments found on DRAMP database
  • ·Literature 1
    • Title

    • An analysis of bacteriocins produced by lactic acid bacteria isolated from malted barley
    • Reference

    • J Appl Microbiol. 2001 Jul;91(1):131-138.
    • Author

    • Vaughan A, Eijsink VG, O'Sullivan TF, O'Hanlon K, van Sinderen D.