• DRAMP ID

    • DRAMP00099
    • Peptide Name

    • Sakacin 5X (Sak5X; Pediocin-like peptide; Bacteriocin)
    • Source

    • lactic acid bacteria (Gram-positive bacteria)
    • Family

    • Belongs to the class IIa bacteriocin
    • Gene

    • Unknown
    • Sequence

    • KYYGNGLSCNKSGCSVDWSKAISIIGNNAVANLTTGGAAGWKS
    • Sequence Length

    • 43
    • Swiss_Prot Entry

    • No entry found
    • Evidence code

    • Unknown
    • Biological Activity

    • Antibacterial, Anti-Gram+, Antimicrobial
    • Target Organism

      • Gram-positive bacteria: Lactobacillus lactis 105, L. collinoides 110, L. brevis 111, L. brevis 112, Pediococcus damnosus 113, P. damnosus 114, Enterococcus faecalis 109.
    • Hemolytic activity

    • Unknown
    • Binding Target

    • Unknown
    • Structure

    • Bridge
    • Structure Description

    • Unknown
    • DRAMP00099 helical wheel diagram
    • Formula

    • C189H296N54O61S2
    • Absent Amino Acids

    • EFHMPQR
    • Common Amino Acids

    • G
    • Mass

    • 5114.22
    • PI

    • 9.33
    • Basic Residues

    • 4
    • Acidic Residues

    • 1
    • Hydrophobic Residues

    • 14
    • Boman Index

    • -34.41
    • Hydrophobicity

    • -15.12
    • Aliphatic Index

    • 70.47
    • Half Life

      • Mammalian:1.3 hour
      • Yeast:3 min
      • E.coli:2 min
    • Extinction Coefficient Cystines

    • 14105
    • Absorbance 280nm

    • 335.83
    • Polar Residues

    • 24

DRAMP00099

DRAMP00099 chydropathy plot
    • No comments found on DRAMP database

  • Literature 1
    • Reference

    • J Appl Microbiol. 2001 Jul;91(1):131-138.
    • Author

    • Vaughan A, Eijsink VG, O'Sullivan TF, O'Hanlon K, van Sinderen D.
    • Title

    • An analysis of bacteriocins produced by lactic acid bacteria isolated from malted barley